Cancer Sage

Cancer Sage and his twin brother Altar Hakurei are the only Saints who survived the last Holy War with Hades in the XV Century.

Holy War of the XV Century
Sage was the Cancer Gold Saint in the fifteenth century (1496, specifically), under the command of Athena. When the Holy War with Hades broke out, he fought the Specters alongside his brother. While his brother Hakurei and the other saints were holding the Wraith just outside the sanctuary, Sage appeared and told him to stop Hakurei get the enemy to the Temple of Athena , beyond the twelve houses. Altar agreed it had confidence in Sage and so the match was on the steps of the Temple. Sage is presumed that at that time he was Athena helping find cloth with which they could beat the Wraith and Hades.

However when everyone believed that the victory had come, the gods appeared Hypnos and Thanatos killing all the other saints, they only thanks to its powerful cosmos and the protection of their goddess survived. So Athena twins chased through The Way of The God and nothing was heard of it.

As Pope
Main Article Pope Sage

Lost Canvas (Manga)
Wise participate in the Holy War against Hades as Gold Saint Cancer and alongside his twin brother, Altar Hakurei. During the conflict, many of their comrades were killed by Hypnos and Thanatos, which act at a distance. Of those dramas and powerlessness then two Saints born a strong desire for revenge from them against Gods Room.

Once the war was won, Hakurei and Sage, the only survivors in the camp of Athena, began preparations for the inevitable next Holy War. Sage becomes the new Pope, despite the fact Hakurei is his elder brother, he wishes indeed remain in the shadows.