Pandora

Pandora is Hades' sister in this life time, at a young age, she opened the box that was sealed by Athena and released Hypnos and Thanatos. She was told that Hades will become her brother and she must protect him until the final battle begins, if she would, they would grant her eternal life. She commands the first wave of Spectres to attack the Sanctuary in the name of Hades in the final chapter. She was given a necklace that allows her to travel through different realms and has a complex relationship with Ikki due to their past regarding Shun. Being Hades' Sister She was her slave and was unable to se fully in color but, after seeing, Ikki's Iron will, She regained Color, Because she gave Ikki the Necklace, she was killed by Thanatos.

The Lost Canvas
In Lost Canvas she is depicted as being so attached to Hades to the point of hysteria and paranoia (Hades defined himself "a bird in a cage"); nevertheless she is a merciless and loyal servant of the god of the Underworld. She used to be a pawn of Hypnos and Thanatos' (whom she was frightened by) schemes, which often put her against her own beliefs and wishes, prompting her to seal Hades away so as to keep him focused on painting the Lost Canvas.

Pandora is crushed upon learning that it had been Alone, not Hades, who had been at her side since they met. With her heart full of sorrow, she departs to find the true Hades, and to punish Alone, whom she hates. She last appeared mobilizing Hades' army, after the defeat of Bennu Kagaho, later, she is enraged by Harpy Valentine's defiance, and aiming to break his will by means of torture, she performs her Noble Venom (ノーブルベノム, Nōburu Benomu) technique on him, which induces excruciating pain. Her attack is negated by the Specter and she is then the victim of his attack; however, she manages to break free and overwhelm Valentine, who is later punished by Rhadamanthys. Pandora then accepts the Underworld commander's apology and afterward encounters Athena, who before engaging her in battle, resurrects her Cloth and dons it. Pandora is later shocked momentarily by the memories Athena caused to flood her by reaching into her heart. She finds out Tenma is Partita's son, her only friend during her childhood. However, years ago, Pandora thought Partita had stolen Hades' soul from his mother. Desperate and confused, she sent the Skeleton soldiers to kill Partita and the newborn Tenma. Yōma then relishes in torturing Pandora psychologically by revealing her that she killed Partita for a crime she never committed, and Partita then embraces her as if to provide her with consolation, only to inflict a murderous stroke instead, which she was able to survive. Pandora then arrives to Uranus and prepares to kill Partita. She is overpowered by the Specter and is mortally wounded by her intense Cosmo burst. Pandora's is then held by Tenma, who protects her by absorbing the impact of Partita's second Cosmo burst with his body. The moribund young woman bears witness to mother and son's battle. After the battle, Pandora reincorporates and sets out to find Alone.

Abilities
Like Athena, she has no physical strength to battle. But has the level of a goddess to control his cosmos with mastery. She wields a trident capable of firing bursts of energy that can break a Golden Armor is very powerful, a ring that also indestructible materealizar serpents that hold the opponent may rely on objects, as he did with his gun. Moreover, its main weapon is a harp, capable of torturing anyone with the music. Above all, Pandora can create explosions cosmos capable of preventing an attack of God. How to escape, Pandora has a speed comparable with that of Knight of the Lion, teleporting the speed of light to anywhere you want. Nevertheless, Pandora can not attack at that speed, losing to Leo in those terms.